International Journal of Computer Applications
Foundation of Computer Science (FCS), NY, USA
|
Volume 75 - Issue 14 |
Published: August 2013 |
Authors: L. Rufus Auxilia, T. Mowna Sundari, Rachel Regi Daniel |
![]() |
L. Rufus Auxilia, T. Mowna Sundari, Rachel Regi Daniel . Molecular Docking Studies of Dolichin A and B, Pterocarpans from Horsegram (Macrotyloma uniflorum) against HIV Replication Enzymes. International Journal of Computer Applications. 75, 14 (August 2013), 19-23. DOI=10.5120/13180-0802
@article{ 10.5120/13180-0802, author = { L. Rufus Auxilia,T. Mowna Sundari,Rachel Regi Daniel }, title = { Molecular Docking Studies of Dolichin A and B, Pterocarpans from Horsegram (Macrotyloma uniflorum) against HIV Replication Enzymes }, journal = { International Journal of Computer Applications }, year = { 2013 }, volume = { 75 }, number = { 14 }, pages = { 19-23 }, doi = { 10.5120/13180-0802 }, publisher = { Foundation of Computer Science (FCS), NY, USA } }
%0 Journal Article %D 2013 %A L. Rufus Auxilia %A T. Mowna Sundari %A Rachel Regi Daniel %T Molecular Docking Studies of Dolichin A and B, Pterocarpans from Horsegram (Macrotyloma uniflorum) against HIV Replication Enzymes%T %J International Journal of Computer Applications %V 75 %N 14 %P 19-23 %R 10.5120/13180-0802 %I Foundation of Computer Science (FCS), NY, USA
Isomeric pterocarpans, Dolichin A and Dolichin B of Macrotyloma uniflorum were docked with the three replication enzymes of HIV (Reverse transcriptase, Protease, Integrase). Analysed results proved that the docking score was high for Protease with Dolichin A (-6. 6899) and Dolichin B (-6. 6944) among Reverse transcriptase and Integrase. AIDS therapies could be scrutinized and /or replaced after the successful inihibitory effect of Dolichin. This study will support the cutting edge of HIV research and drug designing to find out a less side effect causing herbal formulations.